Buy Tesamorelin
In 2026, Tesamorelin is a synthetic peptide and growth hormone-releasing hormone (GHRH) analog primarily used to treat HIV-associated lipodystrophy. It works by stimulating the pituitary gland to produce and release the body’s own growth hormone, which helps specifically target and reduce stubborn visceral (deep abdominal) fat.
Core Medical Uses
- HIV-Associated Lipodystrophy: It is the only FDA-approved medication for reducing excess abdominal fat in adults with HIV who have developed lipodystrophy (an abnormal distribution of body fat caused by some antiretroviral therapies).
- Visceral Fat Reduction: Unlike standard weight-loss drugs, Tesamorelin specifically targets the “hard” fat wrapped around internal organs rather than “soft” subcutaneous fat under the skin.
Mechanisms & Benefits
- Growth Hormone Stimulation: It mimics the natural hypothalamic hormone (GHRH), triggering the release of endogenous growth hormone and subsequently increasing IGF-1 levels.
- Metabolic Optimization: Beyond fat loss, it is researched for improving lipid profiles (lowering triglycerides), enhancing insulin sensitivity, and supporting lean muscle
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- Cognitive Research: Studies in 2026 continue to investigate its potential neuroprotective effects, including favorable outcomes on executive function and memory in healthy older adults and those with mild cognitive impairment.
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Administration and Formulations
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- Formulations: In 2026, a new concentrated formulation, Egrifta WR (approved March 25, 2025), is replacing the older Egrifta SV. This new version requires only weekly reconstitution and a much smaller injection volume, improving patient convenience and adherence.
- Method: Administered via daily subcutaneous injection into the abdominal area.
- Sustained Use: Benefits typically only last as long as the medication is continued; visceral fat often re-accumulates if treatment is stopped.
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Safety and Side Effects
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- Common Side Effects: Injection site reactions (redness, itching, pain), joint pain (arthralgia), muscle pain (myalgia), and swelling in the hands or feet (peripheral edema).
- Serious Risks: It may increase blood sugar levels, raising the risk for type 2 diabetes. It is strictly contraindicated during pregnancy and for individuals with active cancer.
- Athletic Status: It is a prohibited substance in competitive sports at all times by the World Anti-Doping Agency (WADA).
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