Buy SLU-PP-332

Core Mechanisms

• Exercise Mimicry: SLU-PP-332 tricks the body’s high-energy tissues—like skeletal muscle and heart tissue—into acting as though they are undergoing intense aerobic exercise.
• Mitochondrial Biogenesis: It activates the PGC-1α/ERRα axis, which triggers the creation of new mitochondria and enhances the efficiency of existing ones.
• Metabolic Shift: The compound promotes a shift in cellular fuel preference toward fatty acid oxidation (fat burning) rather than glucose storage, similar to metabolic changes seen during fasting or steady-state cardio. 

Primary Research & Clinical Benefits

• Significant Weight Loss: Obese mice treated with the compound lost approximately 12% of their body weight in one month without changes in food intake or physical
  • activity.
  • Enhanced Endurance: Treated mice showed a nearly 50% increase in running endurance and a shift toward fatigue-resistant “slow-twitch” oxidative muscle fibers.
  • Metabolic Syndrome Alleviation: It improves insulin sensitivity, lowers fasting blood glucose, and reduces fat accumulation in the liver (addressing conditions like NAFLD/MASH).
  • Organ Protection: Emerging 2026 research indicates it may reverse mitochondrial damage and inflammation in aging kidneys and strengthen heart muscle in cases of heart failure. 

  Current Status and Safety 

  • Safety, long-term side effects, and exact human dosages remain unknown.
  • Next Generations: Researchers are refining the molecule to improve oral
  • bioavailability (turning it into a pill rather than an injection) and seeking “isoform-selective” versions to reduce potential side effects like cardiac hypertrophy.
  • Availability: While it has gained interest in “biohacking” and longevity communities, experts emphasize that it is not a replacement for the holistic benefits of actual physical movement.