BUY NAD+

Core Mechanisms & Importance

• • • Cellular Battery: NAD+ fuels the mitochondria, enabling cells to produce energy, repair DNA, and maintain systemic homeostasis.
    • Longevity Proteins: It serves as an essential co-substrate for Sirtuins (longevity genes that regulate cellular aging) and PARPs (enzymes that detect and fix DNA damage).
    • Natural Decline: NAD+ levels peak in early adulthood and drop drastically with age—often by 50% or more by age 50. This decline is a primary driver of age-related issues like chronic fatigue, brain fog, and metabolic dysfunction. 

Primary Wellness & Clinical Uses 

• • Regulatory & Safety Status

    • FDA Status: As of 2026, NAD+ is regulated as a supplement, not a medication. While generally recognized as safe, it is not FDA-approved for treating specific diseases.
    • WADA/Sports: NAD+ itself is not a banned substance. However, WADA generally prohibits IV infusions over 50mL for competitive athletes unless required for a documented medical treatment.
    • Side Effects: Usually mild, but high doses or rapid IV infusions can cause temporary nausea, head pressure, or heart palpitations. Energy & Cognition: Used to combat fatigue and “brain fog” by improving mitochondrial efficiency and neuronal health.
      • Metabolic Health: Supplementation is studied for its ability to improve insulin sensitivity, enhance fat metabolism, and support healthy weight maintenance.
      • Skin Health: Topical and injectable forms are used in aesthetics to boost collagen synthesis, strengthen the skin barrier, and reduce inflammation.
      • Addiction Recovery: High-dose IV protocols are increasingly utilized to reduce cravings and withdrawal symptoms by restoring brain chemistry in substance abuse cases.
      • Cardiovascular Support: Emerging research suggests it may reduce arterial stiffness and lower systolic blood pressure in older adults. 

      Administration Methods

      • Oral Precursors (NR/NMN): These smaller molecules, such as Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN), are more stable for oral use and are converted into NAD+ inside the cells.
      • NAD+ IV Drip: Considered the “gold standard” for rapid restoration, providing 100% bioavailability by bypassing the digestive system.
      • NAD+ Injections: Subcutaneous or intramuscular shots offer a fast-acting alternative to pills and are more convenient than lengthy IV sessions.